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Vivitrol Injection: Uses, Dosage, Side Effects, Warnings

Do not take any cough medicine with codeine in it while you are taking naltrexone. Naltrexone can cause or worsen withdrawal symptoms in people who take narcotics. You must stop taking all narcotics 7 to 10 days before you start taking naltrexone. Of the three drugs approved by the FDA to treat alcoholism, only Antabuse is an abstinence-based medication, meaning its intent is to prevent an individual from drinking. The long-acting form of naltrexone may improve treatment strategies for people with alcohol dependence by eliminating the medication compliance issue. If you believe that you have an alcohol or opioid use disorder or want to cut back on your use, talk to your doctor about your treatment options.

Comparative rates of family history of alcoholism between men and women, however, were not given. Hence, future studies testing the efficacy of Vivitrex®/Vivitrol® should investigate any potential interaction between familial alcoholism (or related variables including age of alcoholism onset) and treatment outcome. A single-site, 6 week, open-label trial studied 16 alcohol-dependent individuals who were given a single intramuscular dose of Naltrel® (300 mg) (Galloway et al 2005). Also, the trend was for participants’ drinking outcomes to improve between enrollment and the end of the trial (Galloway et al 2005). Before initiating treatment with injectable naltrexone, your healthcare provider will perform a physical exam, may determine your liver function, and conduct a drug test. Because naltrexone is an opioid antagonist, taking it may lead to opioid withdrawal if you have taken an opioid medication within the last 10 days.

Chronic Pain

It’s time to make a change and reclaim your life from addiction. Like naltrexone, acamprosate seems to work best for people who are able to stop drinking before starting treatment. When you have alcohol use disorder, just thinking about alcohol triggers a pleasurable response in the brain. This drug may be a good choice when someone has gotten an ultimatum from their family, an employer, or the legal system about their alcohol misuse. “You can commit to taking Antabuse every day while the other person watches,” he says.

Your doctor can talk about a medication’s pros and cons, availability, and more with you. The overdose risk is higher at these times because Vivitrol isn’t working as well or at all to stop your cravings. So taking the same doses of opioid medications that you took before starting to use Vivitrol may cause serious overdose or even death. Naloxone (Narcan), on the other hand, is a medication that’s used to treat opioid overdoses. This medication stops the “high” feeling you may get from opioids.

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The importance of the findings of allergic-type interactions with Vivitrex® is uncertain. Based upon the two cases of pneumonia reported by Garbutt et al (2005) and the one case of angioedema reported by Johnson et al (2004), the allergic-type reaction rate for Vivitrex®/Vivitrol® would be 1 per 218 study subjects. Additional investigation of oral naltrexone and naloxone (a structurally similar medication designed for intravenous injection) is needed to determine their allergic-type reaction rates. Comparing the Vivitrex®/Vivitrol® findings directly with any such results, however, would be complicated by differences in study population size, disease states, and length of exposure, among other factors.

  • Sometimes you may have symptoms so severe that you need to go to a hospital.
  • Continually facing the consequences of alcohol dependence can be a challenge, but you are not alone.

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